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TP53 and FGFR3 Gene Mutation Assessment in Urine: Pilot Study for Bladder Cancer Diagnosis.

Identifieur interne : 000152 ( France/Analysis ); précédent : 000151; suivant : 000153

TP53 and FGFR3 Gene Mutation Assessment in Urine: Pilot Study for Bladder Cancer Diagnosis.

Auteurs : Nicolas Noel [France] ; Jerome Couteau [France] ; Geraldine Maillet [France] ; Françoise Gobet [France] ; Françoise D'Aloisio [France] ; Christophe Minier [France] ; Christian Pfister [France]

Source :

RBID : pubmed:26254388

English descriptors

Abstract

To assess, in a prospective clinical research study, a new non-invasive and reliable test to accurately detect tumor protein 53 (TP53) and fibroblast growth factor receptor-3 (FGFR3) mutations in cells in urine.

PubMed: 26254388


Affiliations:


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pubmed:26254388

Le document en format XML

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<name sortKey="Noel, Nicolas" sort="Noel, Nicolas" uniqKey="Noel N" first="Nicolas" last="Noel">Nicolas Noel</name>
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<nlm:affiliation>Department of Urology, Rouen University Hospital, Rouen, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Urology, Rouen University Hospital, Rouen</wicri:regionArea>
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<nlm:affiliation>TOXEM Laboratory, Le Havre, France.</nlm:affiliation>
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<name sortKey="Pfister, Christian" sort="Pfister, Christian" uniqKey="Pfister C" first="Christian" last="Pfister">Christian Pfister</name>
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<title level="j">Anticancer research</title>
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<term>DNA Mutational Analysis</term>
<term>Electrophoresis, Agar Gel</term>
<term>Humans</term>
<term>Mutation (genetics)</term>
<term>Neoplasm Staging</term>
<term>Phenotype</term>
<term>Pilot Projects</term>
<term>Receptor, Fibroblast Growth Factor, Type 3 (genetics)</term>
<term>Receptor, Fibroblast Growth Factor, Type 3 (urine)</term>
<term>Tumor Suppressor Protein p53 (genetics)</term>
<term>Tumor Suppressor Protein p53 (urine)</term>
<term>Urinary Bladder Neoplasms (genetics)</term>
<term>Urinary Bladder Neoplasms (pathology)</term>
<term>Urinary Bladder Neoplasms (urine)</term>
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<term>Mutation</term>
<term>Urinary Bladder Neoplasms</term>
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<term>Urinary Bladder Neoplasms</term>
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<keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en">
<term>Receptor, Fibroblast Growth Factor, Type 3</term>
<term>Tumor Suppressor Protein p53</term>
<term>Urinary Bladder Neoplasms</term>
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<term>DNA Mutational Analysis</term>
<term>Electrophoresis, Agar Gel</term>
<term>Humans</term>
<term>Neoplasm Staging</term>
<term>Phenotype</term>
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<div type="abstract" xml:lang="en">To assess, in a prospective clinical research study, a new non-invasive and reliable test to accurately detect tumor protein 53 (TP53) and fibroblast growth factor receptor-3 (FGFR3) mutations in cells in urine.</div>
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<affiliations>
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<li>Le Havre</li>
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<name sortKey="Noel, Nicolas" sort="Noel, Nicolas" uniqKey="Noel N" first="Nicolas" last="Noel">Nicolas Noel</name>
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<name sortKey="Couteau, Jerome" sort="Couteau, Jerome" uniqKey="Couteau J" first="Jerome" last="Couteau">Jerome Couteau</name>
<name sortKey="D Aloisio, Francoise" sort="D Aloisio, Francoise" uniqKey="D Aloisio F" first="Françoise" last="D'Aloisio">Françoise D'Aloisio</name>
<name sortKey="Gobet, Francoise" sort="Gobet, Francoise" uniqKey="Gobet F" first="Françoise" last="Gobet">Françoise Gobet</name>
<name sortKey="Maillet, Geraldine" sort="Maillet, Geraldine" uniqKey="Maillet G" first="Geraldine" last="Maillet">Geraldine Maillet</name>
<name sortKey="Minier, Christophe" sort="Minier, Christophe" uniqKey="Minier C" first="Christophe" last="Minier">Christophe Minier</name>
<name sortKey="Pfister, Christian" sort="Pfister, Christian" uniqKey="Pfister C" first="Christian" last="Pfister">Christian Pfister</name>
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